Effects of spirulina on hypercholesterolemia and fatty liver in rats

T. Kato and K. Takemoto. 1984. Saitama Medical College, Japan.

Rats fed basal diets containing 1% cholesterol showed elevated total cholesterol, and phospholipids in serum. This was clearly reduced by rats fed basal diets containing 16% spirulina and 1% cholesterol. The results indicated spirulina may prevent dietary hypercholesterolemia and arterioscelerosis. Fatty liver caused by high fat and high-cholesterol diets was also reduced rapidly by feeding spirulina.

PUB: in Japan Nutr. Foods Assoc. Journal. 37:323.


Effects of Spirulina platensis on plasma lipoprotein lipase activity in fructose-induced hyperlipidemic rats.

Iwata K, Inayama T, Kato T.

Laboratory of Nutrition, Kagawa Nutrition College, Tokyo, Japan.

The effects of Spirulina platensis on lipoprotein lipase activity and hepatic triglyceride lipase activity in post-heparin plasma were studied in fructose-induced hyperlipidemic rats. Male Wistar rats aged 3 weeks old (body weight, 54 g) were fed on the high-fructose diet (68%) or the high-fructose diets containing Spirulina at the level of 5, 10, and 15%, respectively, for 4 weeks. The dietary hyperlipidemia caused by the high-fructose diet was improved by Spirulina feeding, accompanied by a significant increase in the lipoprotein lipase activity in post-heparin plasma.

PUB: J Nutr Sci Vitaminol (Tokyo). 1990 Apr;36(2):165-71.

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